“Are You M.A.D.? 

An axis awry of
Mast cell activation disease,
Autonomic neuropathy and
Disorders of connective tissue"

Sunday, May 19, 2024, 4 p.m. Eastern Time

Dr. Anne Maitland

A growing body of evidence is linking heritable disorders of connective tissue, such as Ehlers Danlos Variants, with dysautonomia and mast cell dysfunction, which lead to chronic fatigue, brain fog, irritable bowel symptoms and pain syndromes. Dr. Maitland will present a brief review of the diagnosis and relationships of this clinical triad, MCAD, Autonomic dysfunction, and Disorders of connective tissue or hEDS. A better understanding of these relationships should lead to multi-disciplinary clinical therapies to help right this trio of modern day epidemics.


Director, Allergy & Immunology Services
Metrodora Institute

Asst Professor, Icahn School of Medicine, at Mt. Sinai, Department of Medicine- Division of Allergy & Clinical Immunology

Dr. Maitland is board-certified in allergy & immunology and internal medicine. As an allergy/immunology specialist at Metrodora Institute, Dr. Maitland’s clinical and research efforts are focused on increasing access to allergy and immunology specialty care. She is also one of the country’s top experts in immune-mediated disorders, including mast cell disease (MCD). She also serves on the scientific faculty for the Mast Cell Disease Society, the Ehlers-Danlos Society’s International Consortium and the Chiari-Syringomyelia Foundation.

She previously served as the medical director of Comprehensive Allergy & Asthma Care in New York and Assistant Professor in the Department of Medicine, Allergy and Clinical Immunology at the Icahn School of Medicine at Mount Sinai.

She received her MD and PhD at the University of Pennsylvania, and copleted her residency in Internal Medicine at Brigham and Women’s Hospital. She completed a Fellowship in Allergy & Immunology at Brigham and Women’s Hospital and Mount Sinai Hospital.