Further evaluation

Further evaluation should include:

• A follow-up of any abnormalities found on the initial workup to determine if there are other causes of chronic fatigue or other symptoms
• Appropriate referrals to specialists after the initial workup
• Immune Dysfunction testing (often available only through research centers and Immunology physicians) to look for infectious agents such as EBV, HHV-6, and other humeral immune evaluations (IgG, IgM, IgA, IgE, IgG subclass, T-cell subset evaluation), and innate immune responses (anti-inflammatory mediators, lymphokines). Finding a center to do this testing may be difficult because despite the recommendation coming repeatedly from the CFS Advisory Committee, Centers of Excellence for CFS still have not been created and funded.